Multi-purpose Recombinant Human Alpha-galactosidase A/gla Protein (his Tag) In Multiple Colors [goZCOqrw]

Recombinant Human Alpha-Galactosidase A Protein

Our Recombinant Human Alpha-Galactosidase A Protein (His Tag) is a highly purified, recombinant protein derived from HEK293 cells. This protein is a lysosomal enzyme that plays a crucial role in the treatment of Fabry disease, a rare X-linked sphingolipidosis. With a calculated molecular weight of 46.4 kDa and an observed molecular weight of 50-60 kDa, this protein is designed to provide a reliable and effective solution for enzyme replacement therapy. Key features include:

• Expression Host: HEK293 Cells
• Sequence: Leu32-Leu429
• Tag: C-His

Product Specifications and Benefits

Our Recombinant Human Alpha-Galactosidase A Protein is produced with exceptional purity, exceeding 95% as determined by reducing SDS-PAGE. It is also tested for endotoxin levels, ensuring a safe and reliable product. The protein is supplied as a 0.2 μm filtered solution in 20mM Tris-HCl, 150mM NaCl, pH 8.0, making it easy to reconstitute and use in various applications. Benefits include:

• High purity and endotoxin-free
• Stable storage at < -20°C for up to 6 months
• Convenient formulation for easy reconstitution

Practical Applications and Background

The Recombinant Human Alpha-Galactosidase A Protein is an essential tool for researchers studying Fabry disease and related conditions. As a lysosomal enzyme, it is involved in the hydrolysis of glycolipids and glycoproteins, playing a critical role in the treatment of Fabry disease. This protein is ideal for use in enzyme replacement therapy, providing a reliable and effective solution for patients with this rare condition. Background information:

• Alpha-Galactosidase A is a homodimeric glycoprotein belonging to the glycosyl hydrolase 27 family
• Used in long-term enzyme replacement therapy for Fabry disease
• Defects in Alpha-Galactosidase A lead to the accumulation of glycolipids in various tissues, causing Fabry disease