Bestselling Recombinant Human Vrk1 Protein Accessory [8phn2dv0]

Introducing Bestselling Recombinant Human Vrk1 Protein Accessory [8phn2dv0]

Are you searching for a high-quality recombinant protein that can enhance your research studies? Look no further! Our Bestselling Recombinant Human Vrk1 Protein Accessory [8phn2dv0] is an excellent choice for scientists in various fields. This protein, derived from Baculovirus-Insect Cells, is ideal for applications such as cell signaling, molecular biology, and immunology research.

With a purity of over 95% as determined by reducing SDS-PAGE, our Bestselling Recombinant Human Vrk1 Protein Accessory [8phn2dv0] guarantees the highest level of quality and consistency. This protein has a calculated molecular weight of 45.6 kDa and an observed molecular weight of 47 kDa, making it suitable for various experiments. Its sequence, spanning Met 1 to Lys 396, provides comprehensive coverage of the VRK1 protein.

Key Features and Specifications

• Expression Host: Baculovirus-Insect Cells
• Species: Human
• Accession: Q99986

This protein is also free from endotoxins, ensuring that your experiments are accurate and reliable. It is lyophilized in a sterile 20mM Tris, 500mM NaCl, 10% glycerol buffer, pH 7.4, and may contain 5% - 8% trehalose, mannitol, and 0.01% Tween 80 as protectants.

Practical Applications and Benefits

Our Bestselling Recombinant Human Vrk1 Protein Accessory [8phn2dv0] is a valuable tool for researchers studying cell signaling pathways, particularly those involving the p53/TP53 tumor suppressor protein. This protein phosphorylates 'Thr-18' of p53/TP53, potentially preventing its interaction with MDM2. As a result, VRK1 plays a crucial role in cell metabolism, cell polarity, apoptosis, and DNA damage response. Moreover, our protein is well-suited for applications in the study of pontocerebellar hypoplasia type 1 (PCH1), a genetic disorder characterized by an abnormally small cerebellum and brainstem, central and peripheral motor dysfunction, and gliosis. By using our Bestselling Recombinant Human Vrk1 Protein Accessory [8phn2dv0], researchers can gain deeper insights into the molecular mechanisms underlying this disease and potentially develop new treatment strategies.