Compact Recombinant Mouse Bmp-4 Protein(n-his)(active) Essentials [HBldbj9c]

Recombinant Mouse BMP-4 Protein (N-His) (Active)

Our Recombinant Mouse BMP-4 protein (N-His) (Active) is a cutting-edge biotechnology product, designed to meet the highest standards of purity and bioactivity. This protein is a member of the transforming growth factor-β (TGF-β) superfamily, playing crucial roles in various developmental processes such as neurogenesis, vascular development, angiogenesis, and osteogenesis. With its exceptional bio-activity, this recombinant protein induces alkaline phosphatase production by ATDC5 cells with an ED₅₀ of <10 ng/mL, ensuring its potent signaling capabilities.

• High Bioactivity: The specific activity of recombinant mouse BMP-4 is > 1 x 10⁵ IU/mg, making it highly effective in various applications.
• High Purity: Our product boasts a purity of > 98%, as determined by reducing SDS-PAGE, ensuring reliability and consistency.

Product Properties and Specifications

This recombinant protein is produced in E. coli, offering a cost-effective and scalable production process. It is characterized by a sequence from Lys 303 to Arg 408 and has an observed molecular weight of 11-17 kDa. The protein is tagged with a C-His tag, which aids in purification and detection. The bio-activity of this protein is verified by its ability to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction, demonstrating its multifaceted biological functions.

• Expression Host: E. coli
• Sequence: Lys 303-Arg 408
• Tag: C-His

Practical Uses and Benefits

The Recombinant Mouse BMP-4 protein (N-His) (Active) is an invaluable tool for researchers and scientists in various fields, including developmental biology, cell culture, and drug discovery. Its high bioactivity and purity make it suitable for a wide range of applications, such as:

• Neurogenesis: Studying the development of nervous tissue and neural pathways.
• Vascular Development: Investigating the formation and maintenance of blood vessels.
• Angiogenesis: Exploring the process of new blood vessel formation in various diseases.

By using this product, researchers can gain valuable insights into the complex mechanisms of cell signaling and development, ultimately leading to advancements in medical research and drug development.