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Recombinant Mouse IL-3 Protein (N-His) (Active)

Introducing our high-quality Recombinant Mouse IL-3 Protein (N-His) (Active), a crucial component for various research applications. This protein is a pleiotropic factor produced primarily by activated T cells, capable of stimulating the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. Its diverse functions and targets make it a valuable tool in the field of immunology and cellular biology. Key features include:

• Produced in E. coli expression system for high purity and activity.
• Tagged with C-His for easy detection and purification.
• Meets the highest standards of quality control, ensuring reliable results.

Product Properties and Specifications

Our Recombinant Mouse IL-3 Protein (N-His) (Active) boasts exceptional purity, exceeding 98% as determined by reducing SDS-PAGE. It is free from endotoxins, with a level less than 0.1 EU per μg of the protein, ensuring minimal interference in your experiments. The protein is lyophilized from sterile PBS, pH 7.4, with added protectants such as trehalose, mannitol, and Tween 80 to maintain stability during storage. Key specifications include:

• Calculated molecular weight: 16.0 kDa
• Observed molecular weight: 17 kDa
• Bio-activity: Induces NFS-60 cells proliferation with an ED₅₀ < 85 pg/mL

Applications and Benefits

Our Recombinant Mouse IL-3 Protein (N-His) (Active) is an essential tool for researchers studying hematopoiesis, immunology, and cellular biology. It can be used to investigate the effects of IL-3 on various cell types, including hematopoietic stem cells, mast cells, basophils, eosinophils, and macrophages. This protein is also valuable for studying the role of IL-3 in neurotrophic activity and potential associations with neurological disorders. By using our Recombinant Mouse IL-3 Protein (N-His) (Active), you can achieve reliable and reproducible results in your experiments. Target audience includes:

• Immunologists and cellular biologists
• Researchers in the field of hematopoiesis
• Scientists studying neurotrophic activity and neurological disorders