Ultimate Recombinant Mouse Nkg2-d Type Ii Integral Membrane Protein/nkg2d/cd314 (n-6his) Online Exclusive [qvnf1rwx]

High-Quality Recombinant Mouse NKG2-D Protein

Introducing our Recombinant Mouse NKG2-D type II Integral Membrane Protein, a crucial component for research into immune responses and cancer immunotherapy. This protein is a type II transmembrane glycoprotein, belonging to the CD94/NKG2 family, and is expressed on various immune cells, including NK cells and T-cells. Our product offers a reliable source for studying the role of NKG2-D in immunosurveillance and its interactions with ligands on tumor and virus-infected cells.

Key Product Features and Specifications

This recombinant protein is produced in HEK293 cells, ensuring high purity and consistency. It has a calculated molecular weight of 16.7 kDa, with an observed molecular weight ranging from 20-30 kDa. The protein is tagged with N-His, which facilitates purification and detection. Our product meets stringent quality standards, with a purity of >95% as determined by reducing SDS-PAGE and an endotoxin level of <1.0 EU per μg. The protein is lyophilized from a PBS solution, pH 7.4, and is typically formulated with 5%-8% trehalose, mannitol, and 0.01% Tween 80 for stability and protection during storage.

Applications and Benefits

The Recombinant Mouse NKG2-D protein is an essential tool for researchers studying immune responses and cancer immunotherapy. Its ability to stimulate perforin-mediated elimination of ligand-expressing tumor cells makes it particularly valuable for understanding the role of NKG2-D in cytotoxic activity. Additionally, this protein can be used to investigate the activation of NK cells and T-cells, as well as the interaction between NKG2-D and ligands such as MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3, and ULBP4. By using our high-quality recombinant protein, researchers can gain valuable insights into the complex mechanisms of the immune system and develop new strategies for cancer treatment.