Lightweight Recombinant Mouse Cntf Protein(n-his)(active) [limited Qty] [4Mys9DYP]

Recombinant Mouse CNTF Protein (N-His) (Active)

The Recombinant Mouse CNTF protein (N-His) (Active) is a potent neurotrophic factor that plays a crucial role in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. This product is derived from mouse CNTF, a key player in the nervous system, offering a wide range of applications in research and therapy. With its high purity and bio-activity, this protein is ideal for various experimental setups, including cell culture, immunology, and neuroscience studies.

Product Properties and Specifications

The Recombinant Mouse CNTF protein (N-His) (Active) is produced in E. coli and expressed as a His-tagged protein. It has a calculated molecular weight of 23.4 kDa and an observed molecular weight of 17-25 kDa. This protein is highly pure, with a purity level exceeding 98% as determined by reducing SDS-PAGE. It also exhibits low endotoxin levels, less than 0.1 EU per μg, ensuring minimal interference in your experiments. The protein is lyophilized in sterile PBS buffer, pH 7.4, with added stabilizers like trehalose, mannitol, and Tween 80 for enhanced shelf life and reconstituted protein stability.

Applications and Benefits

The Recombinant Mouse CNTF protein (N-His) (Active) is a valuable tool for researchers studying the role of CNTF in neurodegenerative diseases, neuronal differentiation, and cell signaling pathways. This protein can be used to induce proliferation in TF-1 cells, demonstrating its bio-activity with an ED₅₀ value less than 10 ng/mL. It is also suitable for generating monoclonal antibodies against CNTF and as a control reagent in immunoassays. This recombinant protein is perfect for anyone seeking high-quality, active CNTF for their research or therapeutic applications, offering a reliable solution for advancing your scientific endeavors.