The Magic Of Recombinant Mouse Artn Protein, Active For Office [bfcMj1Rn]
Product OverviewDescriptionRecombinant Mouse ARTN Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala112-Gly224.Purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLCAccession Q9Z0L2Target SymbolARTNS
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The Magic Of Recombinant Mouse Artn Protein, Active For Office [bfcMj1Rn]
Product Overview
| Description | Recombinant Mouse ARTN Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala112-Gly224. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Accession | Q9Z0L2 |
| Target Symbol | ARTN |
| Synonyms | Artemin; Enovin; Neublastin; ARTNE; EVN; ARTN; NBN |
| Species | Mouse |
| Expression System | HEK293 |
| Tag | N-hFc |
| Expression Range | Ala112-Gly224 |
| Mol. Weight | The protein has a predicted MW of 39.4 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22um filtered solution in 50mM Glycine,150mM NaCl (pH 3.2). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Activity | Immobilized Mouse ARTN, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse GFRA3, His Tag with the EC50 of 32.2ng/ml determined by ELISA. Contact us for detailed testing images. |
| Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping | Shipped at ambient temperature. |
| Gene Background | Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons. |
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