Compact Recombinant Mouse Clec-1 Protein Up To 45% Off [9KbLr5Be]
Product OverviewDescriptionCompact Recombinant Mouse Clec-1 Protein Up To 45% Off [9KbLr5Be] is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln73-Gln269.Purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLCAccession Q8BWY2Target SymbolCLEC
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Product Overview
| Description | Compact Recombinant Mouse Clec-1 Protein Up To 45% Off [9KbLr5Be] is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln73-Gln269. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Accession | Q8BWY2 |
| Target Symbol | CLEC-1 |
| Synonyms | CLEC-1; CLEC1; CLEC1A; MGC34328 |
| Species | Mouse |
| Expression System | HEK293 |
| Tag | N-hFc |
| Expression Range | Gln73-Gln269 |
| Mol. Weight | The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping | Shipped at ambient temperature. |
| Gene Background | C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis. |
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