Name: Experience Recombinant Mouse Ereg Protein Bonkers Deal: 35% Off [ILGJZmp9]
Brand: technovaprecision.com
SKU: HBS15849990936
Price: 56.99 USD
Availability: InStock
Rating: 3.77 (27 reviews)

Experience Recombinant Mouse Ereg Protein Bonkers Deal: 35% Off [ILGJZmp9]

Product Overview

Description	Experience Recombinant Mouse Ereg Protein Bonkers Deal: 35% Off [ILGJZmp9] is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val56-Leu101.
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Accession	Q61521
Target Symbol	EREG
Synonyms	Proepiregulin; EPR; Epiregulin; EREG; ER
Species	Mouse
Expression System	HEK293
Tag	N-hFc
Expression Range	Val56-Leu101
Mol. Weight	The protein has a predicted MW of 32.7 kDa. Due to glycosylation, the protein migrates to 37-40 kDa based on Tris-Bis PAGE result.
Form	Lyophilized
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Endotoxin	Less than 1EU per ug by the LAL method.
Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Shipping	Shipped at ambient temperature.
Gene Background	Epidermal growth factor receptor (EGFR) regulates many crucial cellular programs, with seven different activating ligands shaping cell signaling in distinct ways.EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. As a consequence, EREG or EPGN induce less stable EGFR dimers than EGF-making them partial agonists of EGFR dimerization. Unexpectedly, this weakened dimerization elicits more sustained EGFR signaling than seen with EGF, provoking responses in breast cancer cells associated with differentiation rather than proliferation.