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In Stock Recombinant Mouse Ephb2 Protein Series [A8XrJ9LF]
$49.99
$159.99
-69%
Product OverviewDescriptionIn Stock Recombinant Mouse Ephb2 Protein Series [A8XrJ9LF] is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Leu543.Purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLCAccession P54763Target SymbolEPHB2
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Product Overview
| Description | In Stock Recombinant Mouse Ephb2 Protein Series [A8XrJ9LF] is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Leu543. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Accession | P54763 |
| Target Symbol | EPHB2 |
| Synonyms | DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3 |
| Species | Mouse |
| Expression System | HEK293 |
| Tag | C-His |
| Expression Range | Val19-Leu543 |
| Mol. Weight | The protein has a predicted MW of 59.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping | Shipped at ambient temperature. |
| Gene Background | EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia. |
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