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Honokiol: SIRT3 Activator

Honokiol, also known as NSC-293100, is a potent SIRT3 activator that offers a range of therapeutic benefits. This natural product is formulated as a high-purity powder, ensuring its effectiveness and reliability. With a molecular formula of C₁₈H₁₈O₂ and a CAS number of 35354-74-6, Honokiol stands out for its superior purity, exceeding 98%. It is highly soluble in DMSO, making it easy to dilute and incorporate into various applications.

Product Specifications

This product boasts an impressive formula weight of 266.30 and is stable at -20°C, with a shelf life of over two years. Its formulation as a powder ensures convenient handling and storage. The solubility in DMSO up to 50 mg/ml allows for precise dosing and easy integration into various experimental setups. Key specifications include a purity of >98%, a formula weight of 266.30, and a CAS number of 35354-74-6.

Applications and Benefits

Honokiol's versatility makes it a valuable tool in various research and therapeutic applications. As a SIRT3 activator, it has been shown to enhance mitochondrial oxygen consumption and reduce ROS production, which is particularly beneficial in combating cardiac hypertrophy and improving myocardial and mitochondrial energetics. Its ability to increase SIRT3 expression in the hippocampus can also help alleviate surgery-induced memory loss, neuronal apoptosis, neuroinflammation, and oxidative damage. Additionally, Honokiol promotes insulin sensitivity by increasing the expression of adipocyte gene markers, lipolysis, and glucose transport. These benefits make it an ideal choice for researchers and healthcare professionals seeking a reliable and effective SIRT3 activator.