Most Popular Ibudilast, Neuroinflammation Inhibitor (pde Pan-inhibitor) (tbi2236) Best Choice [Yp6qom75]

Ibudilast: A Cutting-Edge Neuroinflammation Inhibitor

Ibudilast, also known as TBI2236, is a highly effective neuroinflammation inhibitor designed to address a range of neurological conditions. This innovative compound boasts a unique molecular structure, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, which contributes to its potent anti-inflammatory properties. With a purity of over 98%, Ibudilast is formulated as a powder and boasts excellent solubility in DMSO and ethanol, making it versatile for various applications.

• High purity of >98%
• Excellent solubility in DMSO and ethanol

Key Features and Specifications

Ibudilast is a phosphodiesterase inhibitor with selectivity for PDE4 and 5, offering a targeted approach to neuroinflammation. Its unique mechanism of action as a cerebral vasodilator enhances blood flow and relaxation of the intracranial vertebrobasilar artery, contributing to its therapeutic benefits. This compound also exhibits anti-inflammatory effects, enhancing retinal ganglion cell viability in glaucoma and inhibiting glial cell activation. Additionally, Ibudilast has been shown to enhance morphine analgesia while reducing tolerance and withdrawal symptoms.

• Selective phosphodiesterase inhibitor for PDE4 and 5
• Cerebral vasodilator for improved blood flow
• Anti-inflammatory and neuroprotective effects

Applications and Usage Guidelines

Ibudilast's versatile nature makes it suitable for a variety of applications in neuroscience research and clinical settings. To prepare a solution, dissolve Ibudilast in DMSO or ethanol and then dilute to an aqueous buffer. Solutions can be stored at -20°C for up to three months, ensuring long-term stability. With its oral activity and ability to cross the blood-brain barrier, Ibudilast offers a promising treatment option for a range of neurological disorders.

• Orally active and crosses the blood-brain barrier
• Simple and efficient application procedures
• Long-term stability at -20°C