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Fumagillin, MetAP-2 Inhibitor (TBI1146): A Potent Research Tool

Fumagillin, MetAP-2 Inhibitor (TBI1146) is a highly effective research tool designed for the inhibition of MetAP-2, a key enzyme in nucleotide metabolism. This compound, formally known as (2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester, offers a reliable solution for researchers studying various cellular processes. With a molecular formula of C₂₆H₃₄O₇ and a formula weight of 458.54, this inhibitor is available in a pure form of 95% and comes in a convenient powder formulation. Its solubility in DMSO (up to 25 mg/ml) makes it easy to use and integrate into various experimental protocols.

Product Features and Specifications

Fumagillin, MetAP-2 Inhibitor (TBI1146) is a versatile research tool with several notable features. Its high purity ensures consistent and reliable results, while its stable formulation guarantees long-term storage without degradation. The compound's storage conditions are straightforward, requiring storage at -20°C to maintain its stability. With a shelf life of ≥ 2 years, researchers can rely on this product for extended studies. Additionally, the powder form allows for easy handling and precise dosing, which is crucial for achieving accurate experimental outcomes.

Applications and Benefits

Fumagillin, MetAP-2 Inhibitor (TBI1146) finds extensive applications in cellular research, particularly in the study of nucleotide metabolism and related pathways. This inhibitor is ideal for researchers investigating the role of MetAP-2 in various biological processes, such as cell proliferation, apoptosis, and signal transduction. By inhibiting MetAP-2, this compound offers a valuable tool for elucidating the molecular mechanisms underlying these processes. The inclusion of Fumagillin, MetAP-2 Inhibitor (TBI1146) in your research arsenal will provide you with a competitive edge, allowing you to explore new avenues and contribute to the advancement of scientific knowledge.