Xmas Gift Idea Fak Inhibitor 14, Fak Inhibitor (tbi2547) Tool [5ze0YrfS]

FAK Inhibitor 14: A Potent Tool for Targeted Cancer Therapy

The FAK inhibitor 14, also known as TBI2547, is a highly selective and potent inhibitor of focal adhesion kinase (FAK). Designed to target specific cancer pathways, this inhibitor offers a unique advantage over other kinase inhibitors by displaying minimal activity against a range of other kinases, including EGFR, PDGFR, and IGF-RI. This specificity makes it an invaluable tool for researchers and clinicians in the fight against cancer.

• High selectivity for FAK
• Minimal activity against other kinases
• Prevents FAK autophosphorylation

Product Specifications and Storage Details

The FAK inhibitor 14, with the chemical name 1,2,4,5-Benzenetetramine tetrahydrochloride, is provided in a high purity form (>98%). It is available as a powder and has a formula weight of 284.02. The CAS number for this compound is 4506-66-5. The solubility of the product is excellent, as it can be dissolved in DMSO (up to 20 mg/ml) or water (up to 15 mg/ml). It is recommended to store the product at -20°C for stability and longevity, with a shelf life of ≥ 2 years when stored under optimal conditions.

• High purity (>98%)
• Soluble in DMSO and water
• Storage at -20°C for stability

Applications and Benefits

FAK inhibitor 14 is a versatile research tool with a wide range of applications. It is particularly effective in vitro and in vivo studies, where it demonstrates antiproliferative activity against various human tumor cell lines and breast cancer cells. Additionally, the inhibitor has shown promise in reducing the size of pancreatic tumors and glioblastoma, as well as exhibiting antiangiogenic properties. These characteristics make it an excellent choice for researchers in oncology and vascular biology.

• Antiproliferative activity against various tumor cell lines
• Reduction of pancreatic tumors and glioblastoma
• Antiangiogenic activity