Versatile Bongkrekic Acid, Mitochondrial Permeability Pore Inhibitor (tbi2751) Fast Dispatch [cikEJ8QH]

Bongkrekic Acid: Mitochondrial Permeability Pore Inhibitor

Discover Bongkrekic Acid, a cutting-edge mitochondrial permeability pore inhibitor that offers a revolutionary solution for research and therapeutic applications. This potent inhibitor is designed to target and modulate the mitochondrial adenine nucleotide translocase (ANT), effectively preventing the opening of the mitochondrial permeability transition pore. With its high purity of over 98%, Bongkrekic Acid is a reliable tool for scientists seeking to understand and manipulate mitochondrial function.

• High purity: Over 98%
• Formulation: Solution of 1mg/ml in Tris buffer
• Solubility: Miscible with DMSO

Product Specifications and Details

Bongkrekic Acid, formally known as 3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid, boasts a molecular formula of C₂₈H₃₈O₇ (free acid) and a formula weight of 486.60. This compound is readily soluble in DMSO, making it easy to handle and incorporate into various experimental setups. Its stability is ensured with a shelf life of ≥ 1 year when stored at -20°C.

• Molecular Formula: C₂₈H₃₈O₇
• Formula Weight: 486.60
• CAS Number: 11076-19-0

Applications and Benefits

Bongkrekic Acid is a versatile tool for researchers studying apoptosis, cell signaling, and mitochondrial function. Its ability to prevent apoptosis in HeLa cells makes it a valuable tool for understanding the role of mitochondria in cell death. The practical application procedures are straightforward, involving a simple dissolution in DMSO followed by dilution into aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 1 month, ensuring convenience and flexibility in experimental design.

• Inhibits mitochondrial permeability transition pore opening
• Prevents apoptosis in HeLa cells
• Easy to handle and incorporate into various experimental setups