Selling Out Bctc, Trpv1 Blocker (tbi1086) Instant 75% Discount [GBZgqtze]
DescriptionProduct DetailsFormal Name: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamideMolecular Formula: C20H25ClN4OFormula Weight: 372.90CAS Number: 393514-24-4Purity: >98%Formulation: powderSolubility: Soluble in
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Selling Out Bctc, Trpv1 Blocker (tbi1086) Instant 75% Discount [GBZgqtze]
Description
Product Details
Formal Name: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
Molecular Formula: C20H25ClN4O
Formula Weight: 372.90
CAS Number: 393514-24-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
TRPV1 blocker
Functions
Vanilloid receptor I (TRPV1) antagonist, IC50 = 35 nM for capsaicin-induced and 6 nM for acid-induced TRPV1 activation. Displays analgesic activity in rat models of neuropathic pain. Orally active and cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stord at -20°C for up to 2 months.
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