Heavy-duty Rabbit Anti Rhoa Polyclonal Affinity Purified (pbs With 0.05% Sodium Azide And 50% Glycerol, Ph7.4) (western Blot,elisa) Ready To Use [MOiI5m4Q]

Heavy-duty Rabbit Anti Rhoa Polyclonal Affinity Purified (pbs With 0.05% Sodium Azide And 50% Glycerol, Ph7.4) (western Blot,elisa) Ready To Use [MOiI5m4Q] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 50% glycerol, pH7.4 This antibody has been affinity purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse,Rat
• Target: RHOA
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Synthetic peptide of human RHOA
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

This product can be used in analytical tools such as Western Blot,ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.