Must-have Gp000020: Fzd8 (541-549)-d8 Labelled-stf(541) 60% Off - Today Only [GApkIzKJ]

FZD8(UniProt ID Q9H461) synthetic glycopeptide fragment(Thr541-Ala549; UniProt position 541-549, aa length 9) with Sialyl TF (Neu5Acα2-3Galβ1-3GalNAc) at Thr541. Val542 has been labelled with d8. The C-terminus is carboxylic acid. Antiproliferative factor (APF) is a sialoglycopeptide that contains the transmembrane segment of Frizzled 8, a protein encoded by the FZD8 gene. Highly elevated levels of APF have been associated with interstitial cystitis. Abnormal Akt signaling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells. / Frizzled-8; FZD8; APF-d8; Antiproliferative Factor (d8 isotope-labeled synthetic Glycopeptide) / T*V(d8)PAAVVVA-OH H-Thr*-Val-(d8)-Pro-Ala-Ala-Val-Val-Val-Ala-OH where T* = Thr* = Sialyl TF = STF = Neu5Acα2-3Galβ1-3GalNAcα-O-Thr