Smart Percp/cyanine5.5 Anti-mouse Cd278 (icos) Shop The Look [Ps4I1Fi2]

PerCP/Cyanine5.5 Anti-Mouse CD278 (ICOS)

The Smart Percp/cyanine5.5 Anti-mouse Cd278 (icos) Shop The Look [Ps4I1Fi2] antibody is a highly specialized tool for immunological research. Designed to bind with the 47-57 kD ICOS protein, also known as the inducible costimulatory molecule, this antibody is a valuable asset for understanding T cell activation and humoral immune responses. With its exceptional binding affinity and specificity, this antibody is perfect for flow cytometry applications, enabling researchers to detect and analyze ICOS expression on activated T cells and a subset of thymocytes.

Product Specifications and Technical Details

This antibody, clone 7E.17G9, is a monoclonal antibody raised against mouse ICOS. It is conjugated to PerCP-Cyanine5.5, a vibrant fluorochrome that excites at 488 nm and emits at 578 nm, allowing for high-resolution detection. The antibody is produced in a rat host and belongs to the IgG2b isotype with a κ light chain. Its format, PerCP-Cyanine5.5, ensures compatibility with a wide range of flow cytometers. The antibody has been quality tested for flow cytometry applications, ensuring reliable results in your experiments.

Applications and Benefits

The Smart Percp/cyanine5.5 Anti-mouse Cd278 (icos) Shop The Look [Ps4I1Fi2] antibody is ideal for researchers studying T cell biology, particularly in the context of humoral immune responses. It can be used to investigate the role of ICOS in T cell costimulation and proliferation, as well as its involvement in B cell germinal center formation and Th2 cell development. Additionally, the antibody's ability to potentiate TCR-mediated IL-4 and IL-10 production makes it a valuable tool for studying airway tolerance and pulmonary inflammation. Whether you are exploring immune system function or developing new therapeutic strategies, this antibody is a key component of your research toolkit.