Durable Brilliant Violet 711™ Anti-mouse Cd54 Smart Choice [dwuEYxQ7]

Highly Specific Anti-Mouse CD54 Antibody

The Durable Brilliant Violet 711™ Anti-mouse Cd54 Smart Choice [dwuEYxQ7] is a powerful monoclonal antibody designed for researchers studying immune reactions and inflammation. This antibody targets the CD54 molecule, also known as ICAM-1 and Ly-47, which is expressed on various cell types including endothelial cells, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The CD54 molecule plays a crucial role in T cell interactions and lymphocyte trafficking, making it an essential target for immunological research. With its high specificity and reactivity, this antibody is ideal for a range of applications in flow cytometry.

Product Specifications and Features

The YN1/1.7.4 clone, from which this antibody is derived, has been reported to effectively block the binding of mouse CD54 to LFA-1 and Mac-1, thereby inhibiting cell-cell adhesion and modulating antigen presentation to T cells. This antibody is conjugated to the Brilliant Violet 711™ dye, providing exceptional brightness and multiplexing capabilities. Key features include:

• High Specificity: YN1/1.7.4 clone is known for its high specificity to mouse CD54, ensuring accurate and reliable results.
• Bright Conjugation: The BV711™ dye offers superior brightness, allowing for better detection and analysis in flow cytometry experiments.

Applications and Benefits

The Durable Brilliant Violet 711™ Anti-mouse Cd54 Smart Choice [dwuEYxQ7] is a versatile tool for researchers investigating immune responses and inflammation. Its applications include:

• Flow Cytometry: Ideal for identifying and analyzing CD54-expressing cells in complex samples.
• Immunological Research: Essential for studying T cell interactions, lymphocyte trafficking, and antigen presentation.

This antibody is particularly useful for researchers in immunology, oncology, and infectious diseases, providing valuable insights into the complex dynamics of the immune system.