Experience Apc/fire™ 810 Anti-mouse/human Cd11b Holiday Edition [cdUAzpCv]

APC/Fire™ 810 Anti-Mouse/Human CD11b

The APC/Fire™ 810 Anti-Mouse/Human CD11b antibody, clone M1/70, is a highly specific monoclonal antibody designed to detect CD11b in various applications. This antibody, produced by BioLegend, is an essential tool for researchers studying immune cell interactions and signaling pathways. With a wide reactivity range encompassing mouse, human, cynomolgus, and rhesus species, this antibody offers versatility for cross-species analysis. The APC/Fire™ 810 conjugate provides bright and stable fluorescence, making it ideal for flow cytometry and other imaging techniques.

Product Features and Specifications

This monoclonal antibody recognizes the CD11b glycoprotein, also known as αM integrin, Mac-1 α subunit, and several other aliases. CD11b is a crucial molecule expressed on various immune cells, including granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. The association of CD11b with CD18 (β2 integrin) forms the Mac-1 complex, which plays a pivotal role in cell-cell interactions by binding to ligands such as ICAM-1, ICAM-2, ICAM-4, iC3b, and fibrinogen. The M1/70 clone exhibits excellent specificity and sensitivity, ensuring reliable detection and minimal cross-reactivity. The antibody is available in a convenient format of APC-Fire 810, offering a vibrant and bright signal for enhanced data visualization.

Practical Applications and Benefits

The APC/Fire™ 810 Anti-Mouse/Human CD11b antibody is ideal for a range of applications, including flow cytometry and immunohistochemistry. Its reactivity across multiple species allows for broad compatibility in various experimental settings. The product's regulatory status as RUO (Research Use Only) ensures it is suitable for use in research and development without the constraints of clinical applications.

• Enhanced Visualization: The APC/Fire™ 810 conjugate provides bright and stable fluorescence, allowing for clearer and more detailed imaging of CD11b-expressing cells.
• Specificity: The M1/70 clone offers high specificity for CD11b, reducing the chances of false-positive results and ensuring accurate data interpretation.

This antibody is a valuable asset for researchers investigating the role of CD11b in immune responses and cellular interactions.