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PE Anti-Human CD318 (CDCP1)

The PE Anti-Human CD318 (CDCP1) antibody is a powerful tool for researchers studying hematopoietic progenitor cells and various cell types. This monoclonal antibody recognizes CD318, also known as CDCP1, CUB domain containing protein 1, and SIMA135, a transmembrane protein with significant applications in cell biology research. With a predicted molecular weight of approximately 93 kD and three CUB domains, CD318 plays a crucial role in early hematopoiesis and is expressed in a wide range of cell types, including keratinocytes, skeletal muscle, colon, kidney, lung, and small intestine.

Product Specifications and Details

The PE Anti-Human CD318 (CDCP1) antibody, clone CUB1, is a mouse monoclonal antibody that is highly reactive with human CD318. This antibody is conjugated with PE, a vibrant fluorescent dye, making it ideal for flow cytometry applications. Key features of this product include its format, host, isotype, and applications. It is available in a PE-conjugated format, produced by a mouse host, and belongs to the IgG2b κ isotype. This antibody has been quality tested for flow cytometry applications, ensuring its reliability and effectiveness.

Applications and Benefits

The PE Anti-Human CD318 (CDCP1) antibody is an essential tool for researchers investigating the role of CD318 in various cellular processes. Its overexpression in colon and lung tumors, particularly its correlation with metastatic ability, makes it a valuable marker for cancer research. The antibody's ability to recognize CD318 in different cell types, including mesenchymal stem cells and neural progenitor cell populations, makes it a versatile reagent for a wide range of studies. By using this antibody, researchers can gain deeper insights into the complex mechanisms of hematopoiesis, cell signaling, and tumor biology.