Viral Apc Anti-mouse Tcr Vγ3 Collection [mCN2cIyE]

APC Anti-Mouse TCR Vγ3: A Key Tool for Research

The APC Anti-Mouse TCR Vγ3 is a highly specialized monoclonal antibody designed for researchers studying γδ T cells, particularly in the context of early fetal thymus development. This antibody is a valuable tool for identifying and characterizing Vγ3⁺ T cells, which are the predominant γδ TCR-bearing cells in early fetal thymus. The majority of CD3⁺ cells in 14-day fetal thymus express Vγ3, making this antibody essential for understanding the development and function of these cells. With its robust reactivity and specificity, the APC Anti-Mouse TCR Vγ3 is a cornerstone in the study of γδ T cell biology.

Product Specifications and Features

The APC Anti-Mouse TCR Vγ3, clone 536, is produced by BioLegend, Inc. and is known under the Garman nomenclature system as the Vγ3 segment. This antibody is also recognized as TCR Vγ5 under the Heilig & Tonegawa nomenclature system. The antibody is conjugated to APC, a fluorochrome that is highly detectable in flow cytometry. It is produced in Syrian Hamster and is of the IgG isotype. The antibody has been quality tested for Flow Cytometry (FC) applications, ensuring its reliability in various experimental settings.

• Reactivity: Mouse
• Format: APC-conjugated

Applications and Benefits

The APC Anti-Mouse TCR Vγ3 is ideal for researchers investigating the development and function of γδ T cells, particularly in the context of early fetal thymus. Its ability to detect Vγ3⁺ T cells makes it a crucial tool for understanding the role of these cells in immune responses and lymphoid organ development. The antibody's specificity and quality-tested FC applications make it a valuable asset in both basic research and clinical studies. Researchers in immunology, oncology, and developmental biology will find this antibody indispensable for their studies, providing them with a deeper understanding of γδ T cell biology and its implications.