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APC Anti-Human/Mouse Integrin β7

The APC Anti-Human/Mouse Integrin β7 is a powerful tool for researchers studying lymphocyte adhesion and migration. This monoclonal antibody, clone FIB504, is designed to specifically bind to integrin β7, a critical component of the α4/β7 and αE/β7 heterodimers. These heterodimers play pivotal roles in lymphocyte adhesion to various ligands, including VCAM-1, MAdCAM-1, and fibronectin, as well as interaction with E-Cadherin. The product is highly versatile, offering reactivity with human, mouse, cynomolgus, and rhesus species, making it a valuable asset for a wide range of research applications.

Product Properties and Specifications

The APC Anti-Human/Mouse Integrin β7 is a monoclonal antibody produced in rats and conjugated to APC. This conjugation provides exceptional fluorescence intensity and is ideal for flow cytometry applications. The antibody is formatted as a liquid, ensuring ease of use and consistent performance. Key features include:

• Host: Rat
• Isotype: IgG2a, κ
• Reactivity: Human, Mouse, Cynomolgus, Rhesus
• Format: Liquid

Applications and Benefits

The APC Anti-Human/Mouse Integrin β7 is a valuable resource for researchers investigating lymphocyte biology and immune system function. Its applications include:

• Flow Cytometry: Quality tested for use in flow cytometry, providing reliable data for lymphocyte analysis.
• Research Areas: Ideal for studying lymphocyte adhesion, migration, and the role of integrin β7 in immune responses.

This product is suitable for researchers in immunology, oncology, and other related fields, offering a reliable and efficient tool for advancing their studies.