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APC Anti-Human CD194 (CCR4)

The APC Anti-Human CD194 (CCR4) antibody is a highly specialized tool designed for researchers studying the complex interactions of the immune system. This monoclonal antibody offers a reliable and efficient way to detect and analyze CD194, also known as CCR4, a key CC chemokine receptor. The antibody's reactivity with human samples ensures compatibility with various immunological assays and research applications.

Product Features and Specifications

The APC Anti-Human CD194 (CCR4) antibody, clone L291H4, is produced by BioLegend, Inc., known for its commitment to quality and reliability. This monoclonal antibody is of the IgG1, κ isotype and is formatted in APC, making it suitable for flow cytometry applications. The host species is mouse, ensuring minimal cross-reactivity. This product is suitable for FC applications, as demonstrated by extensive quality testing.

Practical Uses and Benefits

The APC Anti-Human CD194 (CCR4) antibody is invaluable for researchers investigating the role of CCR4 in various immune responses. Its specificity for human CD194/CCR4 allows for precise analysis of CCR4 expression on T and B cells, basophils, monocytes, and NK cells. This antibody is particularly useful for distinguishing between different Treg populations, with its ability to differentiate between memory-type and CCR4-negative Tregs. By using this antibody, researchers can explore the impact of CCR4 depletion on CD4+ T cell polarization and CD8+ T cell responses, providing insights into the complex immunological mechanisms at play. With its regulatory status as RUO (Research Use Only), this product is suitable for a wide range of experimental settings and research objectives.